Create a respectful and devotional scene inspired by the given biblical verse Genesis 15:3, 'And Abram said, Behold, to me thou hast given no seed: and, lo, one born in my house is mine heir'. The scene should visually depict Abram in prayer or dialogue, with an indication of his despair for not having an heir and his hope in the one who is born in his house. The style of the rendering should be reminiscent of paintings from the Renaissance era showcasing rich, vibrant colors, detailed grandeur, emphasis on light and shadow, all contributing to developing an emotional connection, but no text or words should be incorporated into the artwork.