Matthew 2:21 (KJV) reads, "And he arose, and took the young child and his mother, and came into the land of Israel."

This verse is part of the narrative of the flight into Egypt, where Joseph, Mary, and the infant Jesus flee to Egypt to escape King Herod's decree to kill all male children in Bethlehem. The verse marks the moment when they return to Israel after Herod's death. This verse is significant in the larger context of the Gospel of Matthew, as it reflects the overarching theme of Jesus fulfilling Old Testament prophecies and coming to save his people.

The verse emphasizes the protective role of Joseph, who takes the initiative to bring his family back to Israel. This act signifies Joseph's obedience to God's plan and protection over the child Jesus. Furthermore, it underscores the faith and trust of Joseph and Mary in God's guidance and providence.

The historical context of this verse is crucial to understanding its significance. King Herod's cruel decree to kill the male infants in Bethlehem reflects the political turmoil and oppression that was prevalent during that time. The flight into Egypt and subsequent return to Israel highlight the challenges that the Holy Family faced as refugees, seeking safety and refuge in a foreign land. This context brings depth to the story, showing the vulnerability of the infant Jesus and the hardships faced by his family.

Symbolically, this verse represents the fulfillment of Old Testament prophecies regarding the Messiah. The return of the Holy Family to Israel parallels the Exodus of the Israelites from Egypt, evoking the imagery of God's deliverance and salvation. This underscores Jesus as the new Moses, leading his people out of bondage and into a new promised land. Additionally, the return to Israel marks the beginning of Jesus' earthly ministry, as he comes to fulfill his mission as the Savior of the world.

The theme of divine providence and protection is central to this verse. It shows God's guidance and care for the Holy Family, ensuring their safe return to Israel. This theme resonates throughout the Gospel of Matthew, emphasizing God's sovereignty and intervention in human affairs. The verse also underscores the important role of Joseph as the earthly guardian of Jesus, demonstrating his obedience and faithfulness to God's will.

Moreover, the verse serves as a reminder of the vulnerable state of Jesus as a child, highlighting his humanity and earthly existence. This further emphasizes the significance of Jesus' incarnation and his identification with humanity, as he experiences the hardships and challenges of life.

In conclusion, Matthew 2:21 (KJV) carries profound meaning and significance within the larger narrative of the Gospel of Matthew. It reflects the theme of divine providence, the fulfillment of Old Testament prophecies, and the vulnerability of Jesus as a child. The verse also underscores the faith and obedience of Joseph and Mary, and highlights the political and historical context of Jesus' early life. Overall, this verse serves as a testament to God's plan and protection over his Son, as he comes to fulfill his redemptive mission for humanity.